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Responsable production/ Responsable fabrication H/F

AstraZeneca

Fusion Pharmaceuticals (AstraZeneca) seeks a Director to build and manage an external manufacturing network for PET radiopharmaceuticals across multiple geographies. The role combines technical expertise in radiopharmaceutical operations with strategic partnership development, quality oversight, and cross-functional leadership to support clinical and commercial objectives.

Define and implement external PET manufacturing network strategy aligned to portfolio demand and commercialization timelines

Identify, assess, and select contract manufacturing organizations, nuclear pharmacies, and academic production partners

Lead technical and quality due diligence evaluating cyclotron access, synthesis capability, compliance maturity, and capacity

Oversee process technology transfer and launch readiness to external manufacturing sites

Establish governance and performance management frameworks for external partners including capacity planning and risk mitigation

Advanced degree (PhD, PharmD, or MS preferred) in pharmacy, chemistry, radiochemistry, or pharmaceutical sciences

Significant experience in PET radiopharmaceutical manufacturing or radiopharmacy operations in clinical/commercial settings

Demonstrated leadership building or managing external manufacturing networks and multi-site supply operations

Strong knowledge of PET manufacturing workflows including radionuclide production, synthesis, aseptic filling, and distribution

Deep understanding of GMP, quality systems, and regulatory requirements for radiopharmaceuticals

Experience leading technology transfers, site start-ups, and validation in external manufacturing environments

Proven cross-functional leadership and stakeholder management capability with willingness to travel

Vacancy posted 22 days ago
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