Senior Research Investigator

The Canada Impact+ Research Chairs program is a one-time initiative designed to support institutions in attracting world-leading researchers to address critical national and global challenges. The Impact+ program emphasizes both research excellence and tangible impact. Impact+ Chairs will receive long-term funding and institutional supports that advance ambitious and transformative projects in Canada’s strategic priority areas , build and maintain exceptional research teams, and collaborate with partners across sectors and borders. Impact+ chairholders will drive the translation of discoveries into applications, commercialization and social and economic benefits for Canada and the world, and develop the next generation of highly qualified personnel.
Sinai Health Research and its Lunenfeld-Tanenbaum Research Institute (LTRI) invite applications for full-time, Senior Investigator positions to advance transformational research programs that support the growth of the Canadian economy in one or more of the following priority areas:
Health, including biotechnology
Advanced digital technologies (AI, quantum, cybersecurity)
The nominee’s research area must demonstrably align with one or more of the categories listed above and the research priorities of Sinai Health Research. In addition to Impact+ funding, Sinai Health and LTRI provide competitive institutional support, including research space, access to world-class core facilities, and support for team building and trainee recruitment.
Appointments will be at the rank of Senior Investigator, with an anticipated start date between September 2026 and July 2027. At Sinai Health, Investigator and Senior Investigator are equivalent to tenure-track and senior faculty appointments at major research-intensive universities. Appointments will be associated with an academic appointment (to Associate or Full Professor) to an appropriate University of Toronto department.
Qualifications Successful candidates will have an established, excellent, innovative and internationally recognized research trajectory and an outstanding, independent, externally funded research program. The candidate’s record of excellence in research should be demonstrated by a record of significant, sustained contributions and publications in top-ranked and field-relevant academic journals and internationally ranked presses, participation in professional associations through conference presentations and service work, obtaining competitive funding sources, and strong endorsements by referees of high standing. In keeping with the program’s objectives of research excellence and impact, successful candidates will have a strong record of research impact, including research translation, mobilization, and application with concrete economic and/or social benefits for a range of end users and stakeholders.
Expatriate Canadians wishing to relocate to Canada are encouraged to apply.

A cover letter with a two- to three-page description of research plans for the position and highlighting the specific priority area(s) to which their research relates;
A one-page plan describing actions that will be taken to promote inclusion, diversity, equity, and accessibility within their curriculum, training and/or research design methods, analysis, interpretation and dissemination of research findings and to enhance the rigor, relevance, and accessibility of research outcomes for diverse populations.
All application materials must be submitted through Interfolio:
Review of applications will begin on January 30, 2026, and applicants should endeavor to have submitted all required materials by this date. About Sinai Health and the Lunenfeld-Tanenbaum Research Institute
Sinai Health is a leading academic health sciences centre and a trailblazer for integrated care across the health continuum. Our fusion of science, innovation, care, and learning has earned us international, national, and provincial leadership for unique programs and compassionate care. Sinai Health is one of the top 15 research hospitals in Canada, with leading clinical programs focusing on fetal medicine and women’s health, cancer and cancer genetics, diabetes, autoimmune/inflammatory diseases, complex medicine, complex orthopedics, geriatrics, and infectious disease, and a history of biotech entrepreneurship that ensures the successful application of our research findings. Our Strategic Plan for research leans on our clinical strengths and our discovery and translational research leadership at the Lunenfeld-Tanenbaum Research Institute. LTRI’s faculty members are internationally renowned for their work in network and systems biology, developmental and cellular biology, endocrinology, structural biology, and data science, with a focus on improving human health. LTRI and Sinai Health provide a research-intensive environment with modern, innovative core facilities in the Network Biology Collaborative Centre and The Centre for Phenogenomics , a fully accredited Biospecimen Repository for biobanking, and a dedicated Research Trainee Centre that supports trainees from around the world across disciplines. Our researchers engage in productive collaborations with the broader University of Toronto community and with national and international groups. The University of Toronto boasts one of the world's most concentrated biomedical research communities, and Sinai Health is part of the Toronto Academic Health Science Network ( TAHSN ). Toronto is a vibrant, safe, multicultural city with an excellent quality of life.

Employment at Sinai Health is conditional upon the verification of credentials, completion of a health review, and demonstrating proof of immunity and vaccination status of vaccine-preventable diseases. All employees and affiliates will follow safe work practices and comply with health and safety policies, procedures and training. If you believe you are one of the very few people who may require an exemption from vaccination, supporting medical information must be submitted to our Occupational Health department, who will review and assess.
Sinai Health is comprised of Mount Sinai Hospital, Hennick Bridgepoint Hospital, Lunenfeld-Tanenbaum Research Institute and our system partner Circle of Care. We deliver excellent care in hospital, community and home, focusing on the comprehensive needs of people. Sinai Health discovers and translates scientific breakthroughs, pushes boundaries for health solutions and educates future clinical and scientific leaders. Clinical areas of specialization include rehabilitation and complex continuing care, surgery and oncology, urgent and critical care, and women’s and infants’ health. The Lunenfeld-Tanenbaum Research Institute ranks among the top ten biomedical research institutes in the world. Sinai Health is a full affiliate of the University of Toronto.
As an equal opportunity employer who understands that diversity enriches our community and culture, we invite applications from all qualified candidates including Indigenous Peoples, racialized people, disabled people/people with disabilities, women, and members of 2SLGBTQIA+ communities. If you require accommodation(s) due to disability at any point during the application and hiring process, please contact Klaudia Dudas at Voir email sur nature.com recognize that scholars have varying career paths and that career interruptions due to personal circumstances can be part of an excellent academic record. Candidates are encouraged to explain any personal circumstances to allow for a fair assessment of their application. however, in accordance with Canadian immigration requirements, Canadians and permanent residents will be given priority.

COLLECTION OF EQUITY DATA

As part of your application, you will be asked to complete a brief Diversity Survey directly on the Interfolio site. Results will be aggregated for institutional planning purposes as part of our Equity, Diversity and Inclusion initiatives.