Principal Clinical Scientist

Principal Clinical Scientist (AI Training)
About The Role
What if your decades of clinical trial expertise could directly shape how AI understands and evaluates biomedical evidence for millions of researchers, clinicians, and patients worldwide? We're looking for a Principal Clinical Scientist to bring senior-level authority in clinical trial design and regulatory-grade data interpretation into cutting-edge AI research workflows. Your expertise will help ensure that the AI systems influencing the future of clinical and biomedical science are built on rigorous, accurate, and regulation-ready foundations.This is a fully remote, flexible contract role. No prior AI experience needed — just deep command of clinical trial methodology and regulatory science.Organization: AlignerrType: Hourly ContractLocation: RemoteCommitment: 10–40 hours/weekWhat You'll Do
Design and critically review clinical trial protocols that generate high-quality, regulator-ready datasets for AI training and evaluationInterpret and audit clinical trial results to verify accuracy, consistency, and alignment with regulatory standardsEvaluate AI-generated clinical analyses for scientific soundness and regulatory appropriatenessProvide expert, structured feedback to improve how AI models reason about clinical trial data, endpoints, and outcomesWork independently and asynchronously — fully on your own scheduleWho You Are
Senior-level clinical scientist with hands-on experience designing clinical trial protocols for regulatory submissionDeep expertise interpreting clinical data for agencies such as the FDA, EMA, or equivalent regulatory bodiesStrong grounding in clinical research methodology, biostatistics, or translational scienceNaturally rigorous and detail-oriented — you hold clinical data to the highest standardsClear and precise written communicator who can document scientific reasoning effectivelyComfortable working independently across varied clinical topics and therapeutic areasNice to Have
Prior experience with data annotation, data quality assurance, or evaluation frameworksFamiliarity with AI tools or model evaluation workflows as an end userBackground spanning multiple therapeutic areas or regulatory jurisdictionsExperience in medical writing, evidence synthesis, or systematic reviewWhy Join Us
Work directly on frontier AI systems shaping the future of clinical and biomedical researchFully remote and flexible — work when and where it suits youFreelance autonomy with the structure of meaningful, high-impact scientific workInfluence how AI understands, evaluates, and reasons about real-world clinical evidence at scaleCollaborate with leading AI research teams and labs on genuinely novel challengesPotential for ongoing work and contract extension as new projects launch
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