Principal BU Client Leader

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

Position Description

McKesson is in the business of better health, and we touch the lives of patients in virtually every aspect of healthcare. We partner with payors, hospitals, physician offices, pharmacies, pharmaceutical companies, and others across the spectrum of care to build healthier organizations that deliver better care to patients in every setting. We believe in the importance of strong, vital organizations because we know that patients can only be healthy when our system is healthy.

Every single McKesson employee contributes to our mission—by joining McKesson you act as a catalyst in a chain of events that helps millions of people all over the globe.

Current Need

We are seeking an experienced professional to join McKesson as an Principal BU Client Partner. This highly visible individual contributor role serves as the primary bridge between business leadership and enterprise infrastructure and platform teams.

In this role, you will ensure that infrastructure capabilities are aligned with business priorities from the outset—translating strategy into clear, actionable plans that support growth, modernization, and day-to-day operations. You will bring structure and clarity to how work is planned and prioritized, helping leaders make well-informed decisions about investments, tradeoffs, and risks.

You will drive integrated planning across demand, capacity, cost, and risk—ensuring that initiatives are realistic, well-coordinated, and positioned for successful execution. At the same time, you will provide clear visibility into infrastructure risks, performance, and key dependencies, helping the business make confident, timely decisions.

This role requires a broad understanding of enterprise infrastructure domains (such as cloud, network, platforms, and end-user technologies) and the ability to translate technical concepts into straightforward, business-relevant language. While you will not be responsible for designing or delivering technical solutions, you will play a critical role in aligning business and technical teams to achieve shared outcomes.

You will also serve as the primary relationship lead for the business, establishing consistent engagement, governance, and communication practices that create a seamless experience when working with enterprise infrastructure.

This is an excellent opportunity for a strategic, relationship-focused leader who thrives at the intersection of business and technology and enjoys driving alignment, clarity, and results in a complex, fast-paced environment.

Key Responsibilities

• Build deep understanding of business unit (BU) strategy, priorities, and operating model, and translate that context across infrastructure teams to drive aligned outcomes.
• Develop and drive a multi-year infrastructure roadmap aligned to BU strategy, integrating modernization, growth initiatives, and core operations.
• Partner with BU leadership to embed infrastructure early in planning cycles, enabling proactive engagement, clear prioritization, and value realization.
• Communicate infrastructure strategy, tradeoffs, and business impact to senior stakeholders to support informed decision-making.
• Lead integrated planning by aligning demand, capacity, cost, and risk, ensuring decisions are transparent, governed, and clearly owned.
• Maintain a BU-level infrastructure risk register, ensuring visibility, mitigation planning, and formal acceptance where required.
• Represent BU priorities in enterprise portfolio and capacity planning processes, surfacing resource constraints and cross-initiative dependencies.
• Partner with delivery teams to ensure plans are realistic, risks are managed, and execution is set up for success.
• Align demand with funding and ensure financial discipline across infrastructure investments and cost management.
• Serve as the primary relationship leader and point of entry for the BU, establishing governance, engagement cadence, and alignment with Enterprise Infrastructure and Technology Platforms (EITP) services.

Minimum Requirement

• Degree or equivalent and typically requires 13+ years
• Less years required if has relevant Master's or Doctorate qualifications.

Critical Skills

• Infrastructure literacy across domains
• IT Financial Management
• Executive communication
• Strategic planning
• Ownership and accountability
• Governance and decision management
• Cross-functional coordination
• Technology Risk Management

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$149,600 - $199,500

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson’s (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson’s full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson is committed to being an Equal Employment Opportunity Employer and offers opportunities to all job seekers including job seekers with disabilities. If you need a reasonable accommodation to assist with your job search or application for employment, please contact us by sending an email to (United States) View email address on canada.jobradars.com or (Canada) View email address on canada.jobradars.com. Resumes or CVs submitted to this email box will not be accepted.

Join us at McKesson!